2,3-二氢-5H-噁唑并[2,3-B]喹唑啉-5-酮

2,3-二氢-5H-噁唑并[2,3-B]喹唑啉-5-酮 - Names and Identifiers

Name	2,3-dihydro-5H-oxazolo(2,3-B)quinazolin-5-one
Synonyms	2H-oxazolo[2,3-b]quinazolin-5(3H)-one 2,3-Dihydro-oxazolo[2,3-b]quinazolin-5-one 2,3-DIHYDRO-5H-OXAZOLO[2,3-B]QUINAZOLIN-5-ONE 2,3-Dihydro-5H-oxazolo[2,3-b]quinazolin-5-one 2,3-dihydro-5H-oxazolo(2,3-B)quinazolin-5-one 5H-Oxazolo[2,3-b]quinazolin-5-one, 2,3-dihydro- 2,3-dihydro-5H-[1,3]oxazolo[2,3-b]quinazolin-5-one
CAS	52727-44-3
InChI	InChI=1/C10H8N2O2/c13-9-7-3-1-2-4-8(7)11-10-12(9)5-6-14-10/h1-4H,5-6H2

2,3-二氢-5H-噁唑并[2,3-B]喹唑啉-5-酮 - Physico-chemical Properties

Molecular Formula	C10H8N2O2
Molar Mass	188.18
Density	1.47
Melting Point	160-163°C(lit.)
Boling Point	330°C at 760 mmHg
Flash Point	153.4°C
Vapor Presure	0.000171mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.719

2,3-二氢-5H-噁唑并[2,3-B]喹唑啉-5-酮 - Risk and Safety

WGK Germany

2,3-二氢-5H-噁唑并[2,3-B]喹唑啉-5-酮 - Introduction

2,3-dihydro-5H-oxazolo(2,3-B)quinazolin-5-one(2,3-dihydro-5H-oxazolo(2,3-B)quinazolin-5-one) is an organic compound with the following properties and uses:

Nature:
-Appearance: 2,3-dihydro-5H-oxazolo(2,3-B)quinazolin-5-one is a solid, common white or slightly yellow crystals.
-Solubility: It is soluble in some organic solvents, such as dimethyl sulfoxide (DMSO) and dichloromethane, but its solubility in water is relatively low.

Use:
- 2,3-dihydro-5H-oxazolo(2,3-B)quinazolin-5-one has some biological activities, so it can be used as a pharmaceutical intermediate.
-The compound can also be used as a catalyst in organic synthesis.

Preparation Method:
- 2,3-dihydro-5H-oxazolo(2,3-B)quinazolin-5-one has a variety of preparation methods, one of which is commonly used to synthesize through a multi-step reaction. One method is by first reacting hydrogen cyanide with an anthranilate ester to form an aminobenzoate derivative. The azaquinazoline derivatives are then formed by diazotization and amine reactions. Finally, the final product, 2,3-dihydro-5H-oxazolo(2,3-B)quinazolin-5-one, was obtained by cyclization of ethyl red ketone.

Safety Information:
- 2,3-dihydro-5H-oxazolo(2,3-B)quinazolin-5-one There are currently no detailed safety data and toxicological information publicly available. However, as a laboratory compound, it must be used with appropriate safety measures and under the guidance of qualified personnel.

Last Update：2024-04-09 20:45:29